Factors related to diabetic microangiopathy.

Haemorheological factors in the development of diabetic microangiopathy.

Introduction Diabetic microangiopathy

As a constant evolution in microangiopathy is obviously one of the important features of Diabetes mellitus, different paraclinical approaches have been proposed, and their aspects and results have been presented at this symposium. Several techniques are now available to investigate the anatomical changes of capillaries, such as Vital Capillary Microscopy (Nikolaos Pangratis) allowing to observe...

Regenerative Therapies for Diabetic Microangiopathy

Hyperglycaemia occurring in diabetes is responsible for accelerated arterial remodeling and atherosclerosis, affecting the macro- and the microcirculatory system. Vessel injury is mainly related to deregulation of glucose homeostasis and insulin/insulin-precursors production, generation of advanced glycation end-products, reduction in nitric oxide synthesis, and oxidative and reductive stress. ...

The Comparison of Different Risk Factors which Result in Endothelial Damage Leading to Diabetic Microangiopathy

Chronic endothelial damage plays an important role in the development of angiopathy in diabetes mellitus (1). Since diabetic nephropathy is not determined in forty percent of patients with nonregulated type I diabetes mellitus, it is conceived that the role of hyperglycemia in angiopathy development is not very important. In addition to hyperglycemia, factors such as hypertension, hypercholeste...

Blood glucose control and diabetic microangiopathy.

There is overwhelming evidence that the microangiopathy complications (retinopathy, nephropathy, and neuropathy) of diabetes can be minimised, prevented or improved by optimal blood glucose control. There is little evidence to show otherwise. This paper reviews evidences to demonstrate that poor diabetic control predisposes to diabetic microangiopathy. The only way to minimise diabetic microang...